This is probably do to increased fetal abnormalities. She is a different horse on it - tried all the herbal moody mare oestress type stuff and none of them helped but . I started giving my mare Regumate around 10 months ago when she was diagnosed with Epilepsy which was found to be linked to her coming into season. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate® (altrenogest) Solution 0.22%. The normal rate of early embryoninc loss in healthy mares may be as high as 15% and is higher in older mares. HI, I'm Dr Steve. I do not know the dose of dexamethasone the mare is on, but I . The only mare product to reduce mare issues that has High Dose Vitamin E, 8 herbs, 2 added vitamins and minerals. 10 to 50 µg, IM, q 6 h to 12h. Treated mares received 2 mL Regumate Porcine solution 0.22%/110 lb body weight (2x dosage recommended for estrus suppression) from day 20 to day 325 of gestation. It is the only such medication proven to have progesterone-type biologic activity in the horse. Regumate fans often say it makes the mare feel "content" — their reasoning being that pregnant mares feel "content." Rebreed sooner with early pregnancy detection. For more information on it's use, check out this article on our website: Does My Mare Need Regumate? 20% in fertile mares and over 70% for mares considered to be subfertile. How rapidly does Regumate work? Treatment of pregnant mares with altrenogest is common. in mares that have previously lost their foal to placentitis, although there is not scientific data to support the protocol, is to give these mares, antibiotics and flunixin meglumine, for the first 10 days of the month beginning around the 7th month of gestation. At about $2.50 a day, keeping a mare on this medication can be expensive. Women who are pregnant or suspect they are pregnant should not handle Regu-Mate®. pregnant mares to determine if progesterone levels are adequate to maintain the pregnancy. SPECIAL WARNING (S), IF NECESSARY. In each case the mare was diagnosed pregnant by ultrasound exam at day 14. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. Early in pregnancy progesterone levels above 4.0 . Inside three days of the beginning of remedy, Regu-mate will successfully suppress oestrus in 95 p.c of . It is seen as a panacea for any reproductive problem that results in a mare not carrying a pregnancy to term. Women of child bearing age should exercise extreme caution when handling this product. colic), pregnant mares subjected to lengthy transportation and after manual reduction of a twin pregnancy. No one can say that even after the placenta takes over support of pregnancy that abortion cannot occur later. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate® (altrenogest) Solution 0.22%. Hope this helps! Pregnant women or women who suspect they are pregnant should not handle Regu-Mate®. Pregnant women, or women who suspect they are pregnant, should not handle this product. History of repeated pregnancy loss. Not to be administered by pregnant women. Although weekly Ovu-Mate injections have been used for the maintenance of pregnancy in habitually aborting mares, its use in the maintenance of pregnancy has not yet been established in clinical trials. The proper use of progesterone and Regumate® requires understanding the hormones actions. Consult with your veterinarian for any potential side effect . Ingredients Contains altrenogest 2.2 mg/mL in an oily solution. Quick P4 Equine video Don't lose that foal! pregnancy in mares with low progesterone (Allen 2001). Pregnant women or women who suspect they are pregnant should not handle REGU-MATE® (altrenogest) Solution 0.22%. Buserelin *. Direct contact with the skin should be avoided. TOP TIP you can get regumate porcine which is essentially the same thing but designed for pigs - heaps cheaper - like £60 a bottle and works just as well. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate® (altrenogest) Solution 0.22%. Dosage Administer orally with dose syringe or by placing directly on feed. Treatment of placentitis-affected mares with a double-dose of the oral version of altrenogest "Regumate ® " has been suggested, but while beneficial under the circumstances, the effect of this dosage on "forced" maintenance of an undesirable pregnancy has not been established. The usual dose is 1 ml per 110 lbs body weight once daily for 15 consecutive days. Clinical uses of Regumate® include management of the transition period, suppression of heat in performance mares, and maintenance of pregnancy in problem mares. During pregnancy, the mare mounts a different type of immune response that may allow the cancer or other chronic diseases to worsen. Regumate is the female hormone progesterone used in behaviour modification in mares, geldings and stallions. Dosing cap included, dosing syringe sold separately. Discover if costly regumate therapy is necessary. cycling mares for 7 days following administration of Altrenogest Injection. If she isn't bred, she'll stay out of heat until the CL lyses and the cycle begins again. Like progesterone birth-control pills or implants, it suppresses estrus by tricking the brain into thinking the mare is pregnant. Women of child bearing age should exercise extreme caution when handling this product. Treating foals with immune plasma can modify the problem. Because it can be administered orally and does not interfere with the measurement of naturally produced . Talk to your veterinarian about proper use and safe handling of Regu-Mate®. Lateral Flow Quick P4 RIA Cornell RIA Bet Lab Horse ID Days Pregnant Comments 11.9 13.3 109 162 Regumate & P4 Oil 10.1 9.9 14 230 Regumate & P4 Oil 4.6 6.0 54 186 Regumate & P4 Oil 2.6 6.9 71 297 Regumate & P4 Oil 2.9 4.6 105 232 Regumate & P4 Oil Table 2. Generally, normal pregnant mares do not need supplemental progesterone Pregnant mares with diagnosed low progesterone, a history of pregnancy loss, or those with clinical signs of potential problems may have progesterone prescribed - Regu-Mate® (altrenogest) is a synthetic oral progestagen that is commonly prescribed Possible Side Effects. Natural or synthetic gestagen therapy may exacerbate existing low-grade or "smoldering" uterine inflammation into a fulminating uterine infection in some instances (package insert; Regu-Mate®). Regumate1 contains the drug Altrenogest, a synthetic progestagen, and is labeled for use in mares to suppress estrus (heat) display. If you start it during diestrus, it will prevent your mare from returning to estrus as long as she continues to get a daily dose. It can be given directly by mouth or on your mare's grain ration. Regumate is highly overused and overprescribed. Regumate® is a man made progestane, altrenogest, that has strong progesterone properties and can be placed in the feed. Where any altrenogest-containing product is being administered to pregnant mares as a therapeutic treatment under the prescription of a veterinary surgeon, we would advise that this treatment can continue, in the interests of the welfare of the mare and unborn foal*. This includes mares that are of advanced age, repeated history of unsuccessful foaling outcomes, mares with twin pregnancies, mares that have experienced a significant toxemia, or that suffer significant physical infirmaries including chronic founder, severe arthritis, or body wall injuries or mares that have . When used as directed on the label, Regu-Mate is usually tolerated well by horses. Click to see full answer The Regu-Mate equine dosing device lets you accurately administer Regu-Mate with minimal handling. Regumate Equine is a hormonal medication for mares, distributed in the UK by MSD Animal Health. On average, your mare will be "in heat" (estrus) and under the influence of estrogen for six days. Altrenogest is contraindicated in mares having a previous or current history of uterine inflammation (ie, acute, subacute, or chronic endometritis). Regu-Mate is a solution for oral use only and is available in a 1,000 ml bottle. It is meant to be used for the suppression of estrus in mares. On-site progesterone number in minutes. Women of child bearing age should exercise extreme caution when handling this product. Know when the CL is active. It can be used to prevent or supress the oestrus cycle in mares, restore a regular . Suppression of behavioral estrus, synchronization of estrus, maintenance of pregnancy. 1ml Regumate Equine per 50 kg bodyweight per day for 10 consecutive days. Regumate is the most widely used drug in controlling mare behavior. Regumate Equine 2.2 mg/ml oral solution for horses. Accidental absorption could lead to a disruption of the menstrual cycle or prolongation of pregnancy. Regu-Mate requires a prescription from your veterinarian. Regu-Mate® Solution 0.22%, DIN 00641987, is an oral progestin used to suppress estrus or as an adjunct to help maintain pregnancy in some mares. Apply either at the base of the mare's tongue or directly on her grain. Avoid skin contact. Prudent use of the progestin Regumate can be beneficial in the reproductive management of mares. Meat and offal: 15 days. Regumate is the trade name for a synthetic hormone called altrenogest. 10 to 50 µg, IM, q 6 h to 12h. Mare Support REGUMARE helps support the normal hormonal balance of mares when temperament and marish behaviour adversely affects safe handling, willingness to work or focus in the ring or on the track. Altrenogest is a potent synthetic hormone, is used to control estrus cycles in mares, attain regular breeding cycles in mares, and suppress prolong estrus conditions.Regu-Mate Dosing . It can be effective in quieting a stallion or gelding for show or working situations however it is not effective for a gelding or stallion for long term social pasture situations. GnRH agonist; stimulation of follicular development in . Supports healthy hormone balance in mares for more consistent training and Mares that had twins reduced had a lower live foal rate than mares carrying a singleton pregnancy. It is the only such medication proven to have progesterone-type biologic activity in the horse. Regu-Mate (altrenogest) is a liquid oral medication that provides a synthetic source of progesterone. Within three days of the start of treatment, Regu-mate will effectively suppress oestrus in 95 percent of mares. Because it can be administered orally and does not interfere with the measurement of naturally produced . Regumate is an oral progestagen, allyltrenbolone or altrenogest/ Administration suppresses estrus by forming an artificial luteal period. Kathy St.Martin Equine-Reproduction.com, LLC Equine Reproduction and Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. The most important use for regumate is as a preventative treatment for abortion or placentitis late in pr egnancy. This study provided the following data: 1. Accidental absorption could lead to a disruption of the menstrual cycle or prolongation of pregnancy. Horses: Regu-Mate ® Solution 0.22% is contraindicated in pregnant mares and in mares having a previous history of uterine inflammation (i.e. Regu-Mate altrenogest Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation i.e., acute, subacute, or chronic endometritis. 65% less cost than Regumate. Equine Progesterone Chart Quick P4 Equine Progesterone number […] Regumate is a progesterone. Regu-mate is a synthetic form of progesterone. Unsuccessful breeding? The older the mare was, the more likely she was to lose her pregnancy. ll natural product to help your mare get off hormones and shots. Can use on mares and geldings to calm and relax. WITHDRAWAL PERIOD. GnRH agonist; stimulation of follicular development in . Regu-Mate® is contraindicated for use in mares having a previous or current history of uterine inflammation. Protective gloves should be worn when handling product; women who are pregnant or suspect they are pregnant should not handle Regu-Mate Solution 0.22%. Treated mares received 2 mL Regu-Mate ® (altrenogest) Solution 0.22% /110 lb body weight (2 × dosage recommended for estrus suppression) from day 20 to day 325 of gestation. Twelve mares (Group TREAT) were infected and given . During the 1999 season at ERC, we had 8 cases where EED was diagnosed. Intact skin absorbs Regu-mate. 2013). The active ingredient is altrenogest 2.2 mg/ml. In addition, studies have shown that the product can be used for extended periods without adverse effects on future reproductive performance or fertility.
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